AAV-MEDIATED CRISPR/CAS9 GENE EDITING IN MURINE PHENYLKETONURIA

AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria

Phenylketonuria (PKU) due to recessively inherited phenylalanine hydroxylase (PAH) deficiency results in hyperphenylalaninemia, which is toxic to the central nervous system.Restriction of dietary phenylalanine intake remains the standard of PKU care and prevents the major neurologic manifestations of the disease, yet shortcomings of dietary therapy

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Study on the influence of alumina nanomethanol fluid on the performance, combustion and emission of DMDF diesel engine

With the increasingly strict domestic emission regulations, how to silver lining herbs kidney support reduce diesel emission without affecting its output power has become a hot and important research topic.Due to their unique physical and chemical properties, the combined use of methanol and Al2O3 nanoparticles plays a unique role in promoting comb

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Exogenous DCPTA Increases the Tolerance of Maize Seedlings to PEG-Simulated Drought by Regulating Nitrogen Metabolism-Related Enzymes

2-(3,4-Dichlorophenoxy) triethylamine (DCPTA) regulates plant development; however, the molecular basis of whole wheat phyllo dough this regulation is poorly understood.In this study, RNA sequencing (RNA-seq) analysis and physiological indexes of maize seedlings (three-leaf stage) treated with 15% polyethylene glycol (PEG) with/without DCPTA were i

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